Journal
JOURNAL OF NATURAL PRODUCTS
Volume 73, Issue 2, Pages 247-251Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np900466x
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Funding
- Artsana SpA
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Three new saponins (1-3) and a known saponin, together with four known polyphenolic compounds, have been isolated from the fermented and dried leaves of Fadogia ancylantha (Makoni tea). The structures of compounds 1-3 were established by analysis of their spectroscopic data. Both all ethanol-water extract of F. ancylantha and its phenolic constituents showed significant free-radical-scavenging and antimicrobial activities. No cytotoxicity, its evaluated by analysis of hypodiploid nuclei in HUVEC cells using propidium iodide staining, was observed for either the plant crude extract or its constituents.
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