Journal
JOURNAL OF NATURAL PRODUCTS
Volume 73, Issue 4, Pages 679-682Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np1000297
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Funding
- NIH [ROI Al 039987, CA 122256]
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Three new phorbasides (G-I), chlorocyclopropyl ene-yne macrolide glycosides, were isolated from the sponge Phorbas sp. in yields of 7-9.5 mu g and fully characterized by MS, CD, and microcryoprobe NMR. The structures of the new compounds differ only in the nature of the sugar residues. The absolute configurations of the new compounds were correlated by ROESY and CD with the parent compounds phorbasides A and B.
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