4.7 Article

Sesquiterpenes and Dimeric Sesquiterpenoids from Sarcandra glabra

Journal

JOURNAL OF NATURAL PRODUCTS
Volume 73, Issue 1, Pages 45-50

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/np9006469

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Funding

  1. Key Project of National Natural Science Foundation [30630072, 30721005]
  2. National Science & Technology Major Project [2009ZX09301-001]

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Two new sesquiterpenes, sarcandralactones A (1) and B (2), and five new dimeric sesquiterpenoids, sarcandrolides A-E (3-7), along with 10 known compounds were isolated from the whole plants of Sarcandra glabra. Their structures were elucidated on the basis of spectroscopic analysis. Some of-the new isolates exhibit significant cytotoxicities when tested against a small panel of tumor cell lines.

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