Journal
JOURNAL OF NATURAL PRODUCTS
Volume 72, Issue 6, Pages 1220-1230Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np800740m
Keywords
-
Funding
- Ghent University
- Inbev Baillet Latour Fund
- Fund for Scientific Research - Flanders
Ask authors/readers for more resources
Hop acids, a family of bitter compounds derived from the hop plant (Humulus lupulus), have been reported to exert a wide range of effects, both in vitro and in vivo. They exhibit potential anticancer activity by inhibiting cell proliferation and angiogenesis, by inducing apoptosis, and by increasing the expression of cytochrome P450 detoxification enzymes. Furthermore, hop bitter acids are effective against inflammatory and metabolic disorders, which makes them challenging candidates for the treatment of diabetes mellitus, cardiovascular diseases, and metabolic syndrome. This review summarizes the current knowledge on hop bitter acids, including both phytochemical aspects, as well as the biological and pharmacological properties of these compounds.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available