Journal
JOURNAL OF NATURAL PRODUCTS
Volume 72, Issue 9, Pages 1663-1668Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np9003678
Keywords
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Funding
- National Science Council of Republic of China [NSC98-2320-B002-027-MY3]
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An acetone extract of the fruits of the Taiwanese medicinal plant Schisandra arisanensis has yielded 11 new oxygenated lignans. Four of these, named arisantetralones A-D (1-4), possess the aryltetralone skeleton, while the other seven, named arisanschinins F-L (5-11), are polyoxygenated C-18-dibenzocyclooctadiene lignans. Structures were determined on the basis of spectroscopic analyses, especially 2D-NMR techniques. The structure of compound I was confirmed by X-ray crystallographic analysis. Immunomodulatory activity of the isolated lignans was tested and evaluated.
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