Journal
JOURNAL OF NATURAL PRODUCTS
Volume 72, Issue 9, Pages 1669-1672Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np9003799
Keywords
-
Funding
- National Natural Science Foundation [30630072, 30721005]
Ask authors/readers for more resources
Four new alkaloids, 17-hydroxydaphnigraciline (1), subdaphnidine A (2), daphnezomine L methyl ester (3), and 11-hydroxycodaphniphylline (4), along with 24 known analogues, were isolated from the leaves of Daphniphyllum subverticillatum. The structures of 1-4 were elucidated on the basis of spectroscopic methods and from chemical evidence. Daphnilongeridine (5) showed cytotoxicity against several tumor cell lines at IC50 values in the range 2.4-9.7 mu M and against the HMEC human microvascular endothelial cell line with an IC50 of 2.7 mu M.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available