4.7 Article

Inhibitors of Osteoclast Formation from Rhizomes of Cibotium barometz

Journal

JOURNAL OF NATURAL PRODUCTS
Volume 72, Issue 9, Pages 1673-1677

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/np9004097

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Funding

  1. Vietnam National Project [KC10.20/06-10]
  2. Korea Foundation for International Cooperation of Science & Technology (KICOS)
  3. Korean Ministry of Science & Technology (MOST) in Korea [K2072100000208B010000210]
  4. National Research Foundation of Korea [과09B2106] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Eight compounds (1-8) were isolated from a methanol extract of Cibotium barometz rhizomes including two new furan derivatives, cibotiumbarosides A (1) and B (2), and a new glycoglycerolipid, cibotiglycerol (4). Their structures were elucidated by chemical and spectroscopic methods. Compounds 2-5 each showed inhibition of osteoclast formation with no affect on BMM cell viability.

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