Journal
JOURNAL OF NATURAL PRODUCTS
Volume 72, Issue 6, Pages 1075-1080Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np900016h
Keywords
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Funding
- Australian Postgraduate Award scholarship
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Chemical investigation of the Australian plant Haemodortun simplex resulted in the isolation of three new phenylphenalenones, haemodorone (10), haemodorol (11), and haemodorose (12), together with the previously reported compounds 5, dilatrin (6), and xiphidone (8). The first complete 2D NMR characterization for all of the compounds isolated, including several chemical shift reassignments for dilatrin (6), is reported. In addition this is one of the few reports to discuss the isolation of new phenylphenalenones from an Australian medicinal plant. The crude extract of both the bulbaceous and aerial components of the plant exhibited varying degrees of antibacterial, antifungal, and antiviral activity, and only the bulbs displayed potent cytotoxic activity.
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