☆ 4.7 Article

Okundoperoxide, a Bicyclic Cyclofarnesylsesquiterpene Endoperoxide from Scleria striatinux with Antiplasmodial Activity

JOURNAL OF NATURAL PRODUCTS (2009)

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Journal

JOURNAL OF NATURAL PRODUCTS
Volume 72, Issue 2, Pages 280-283

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/np800338p

Keywords

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Categories

Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy

Funding

  1. National Institutes of Health [TW00327]
  2. Medicines for Malaria Venture, Geneva, Switzerland
  3. United States National Institutes of Health [GM-65597]

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Okundoperoxide (1) was isolated by bioassay-guided fractionation of extracts from Scleria striatinux (syn. S. striatonux). The compound contains a cyclic endoperoxide structural moiety and possesses moderate antimalarial activity.

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