Journal
JOURNAL OF NATURAL PRODUCTS
Volume 72, Issue 3, Pages 581-587Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np8005748
Keywords
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Funding
- National Institute on Drug Abuse [R01 DA 18151]
- Universities of Iowa and Kansas
- NATIONAL INSTITUTE ON DRUG ABUSE [R01DA018151] Funding Source: NIH RePORTER
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Much of what we know about the neurosciences is the direct result of studying psychoactive natural products. Unfortunately, there are many gaps in our understanding of the basic biological processes that contribute to the etiology of many CNS disorders. The investigation of psychoactive natural products offers an excellent approach to identify novel agents to treat CNS disorders and to find new chemical tools to better elucidate their biological mechanisms. This review will detail recent progress in a program directed toward investigating psychoactive natural products with the goal of treating drug abuse by targeting kappa opioid receptors.
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