Journal
JOURNAL OF NATURAL PRODUCTS
Volume 71, Issue 11, Pages 1850-1853Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np800318m
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Funding
- CNR-Rome
- Italian Minister of Foreign Affairs fellowship
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Eleven new thio-avarol derivatives (3-13) were synthesized. Their antimicrobial, brine shrimp lethality, and free-radical scavenging activities and acetylcholinesterase inhibition, together with 12 already reported semisynthetic thioavarol derivatives (14-25), were evaluated. Structure-activity relationships among these thio derivatives were determined.
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