Journal
JOURNAL OF NATURAL PRODUCTS
Volume 71, Issue 4, Pages 706-709Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np070446u
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Eight C-6-geranylflavonoids (1-8) were isolated from an ethanol extract of Paulownia tomentosa fruits. Tomentodiplacone (1), 3'-O-methyl-5'-hydroxydiplacone (2), 3'-O-methyl-5'-O-methyldiplacone (3), and tomentodiplacone B (4) were obtained as new compounds, and 3'-O-methyldiplacol (5) was isolated for the first time from a natural source. The structures of these new compounds were determined by using mass spectrometry (including HRMS) and 1D and 2D NMR spectroscopy, and the absolute configurations of the compounds were determined by circular dichroism. The antibacterial activities of 1-8 against seven bacteria and yeast were evaluated.
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