Journal
JOURNAL OF NATURAL PRODUCTS
Volume 71, Issue 5, Pages 856-860Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np0705054
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Funding
- NCRR NIH HHS [P20 RR 16455-04] Funding Source: Medline
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We previously reported several novel bioactive hybrid polyketide-terpenoid metabolites from a deep water Penicillium rubrum isolated from Berkeley Pit Lake, Butte, Montana. In this paper we report the structures of four new amides, berkeleyamides A-D (1, 4, 5, 7), isolated from extracts of this fungus. The structures of these compounds were deduced by analysis of NMR data, chemical derivatization, and comparison of their spectroscopic data to those of known compounds.
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