Journal
JOURNAL OF NATURAL PRODUCTS
Volume 71, Issue 8, Pages 1479-1480Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np8002707
Keywords
-
Funding
- AstraZeneca
Ask authors/readers for more resources
High-throughput screening of a plant and marine invertebrate extract library to find natural products that inhibit the malarial parasite enzyme target hemoglobinase, II led to the isolation of two new active prenylated chalcones, bipinnatones A (1) and B (2), from aerial parts of the Queensland shrub Boronia bipinnata. Their structures were assigned from interpretation of 2D NMR and high-resolution ESIMS data. Compounds 1 and 2 inhibited hemoglobinase II with IC50 values of 64 and 52 mu M, respectively.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available