Journal
JOURNAL OF NATURAL PRODUCTS
Volume 71, Issue 11, Pages 1887-1890Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np800406q
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Funding
- Swiss National Science Foundation [200020-107775/1]
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Chemical investigation of the methanol extract from the leaves of Arrabidaea patellifera, a Bignoniaceae from Panama, afforded mangiferin, isomangiferin, and six new derivatives (3'-O-p-hydroxybenzoylmangiferin, 3'-O-trans-coumaroyl-mangiferin, 6'-O-trans-coumaroylmangiferin, 3'-O-trans-cinnamoylmangiferin, 3'-O-trans-caffeoylmangiferin, and 3'-O-benzoylmangiferin). All these compounds had antioxidant and radical-scavenging activities, and four of them were relatively active in vitro against Plasmodium falciparum. The structures were determined by spectrometric and chemical methods, including ID and 2D NMR experiments and MS analysis.
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