Journal
JOURNAL OF NATURAL PRODUCTS
Volume 71, Issue 3, Pages 403-408Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np070589g
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An Australian estuarine isolate of an Acremonium sp. (MST-MF588a) yielded the two known compounds 19-O-acetylchaetoglobosin D (1) and 19-0-acetylchaetoglobosin B (2), as the sole cytotoxic principles, along with the known aromatic metabolite RKB 3564S (3), and a novel family of lipodepsipeptides, acremolides A-D (4-7). Structures were assigned to 4-7 on the basis of detailed spectroscopic analysis and chemical derivatization and by application of a new C(3) Marfey's method for amino acid analysis.
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