Journal
JOURNAL OF NATURAL MEDICINES
Volume 64, Issue 3, Pages 275-280Publisher
SPRINGER JAPAN KK
DOI: 10.1007/s11418-010-0402-0
Keywords
Rosa gallica; alpha-Amylase; alpha-Glucosidase; Inhibitor; Hydrolysable tannin; Polyphenol
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The 50% aqueous ethanol extracts of petals of Rosa gallica collected in Xinjiang province, China, exhibited potent inhibitory effects against alpha-amylase and alpha-glucosidase. As the active principles, seven hydrolysable tannins were isolated from this species for the first time and elucidated by NMR and ESI-TOF-MS analysis. Quantitative analysis by ultra-performance liquid chromatography demonstrated that the contents of these hydrolysable tannins were 3-5% of the dry weight of the petals, and the hydrolysable tannins must be related to the medicinal utilization of this species.
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