Journal
JOURNAL OF NATURAL MEDICINES
Volume 64, Issue 3, Pages 358-361Publisher
SPRINGER JAPAN KK
DOI: 10.1007/s11418-010-0407-8
Keywords
Trigonella foenum-graecum; 5,7,3 '-Trihydroxy-5 '-methoxylisoflavone; Orientin-2 ''-O-p-trans-coumarate; Promoting 2BS cell proliferation
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Ten flavonoids were isolated from the ethyl acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum and their structures were elucidated on the basis of spectroscopic methods to be 5,7,3'-trihydroxy-5'-methoxylisoflavone (1), biochanin A (2), formononetin (3), irilone (4), tricin (5), daidzein (6), calycosin (7), orientin-2aEuro(3)-O-p-trans-coumarate (8), vitexin-2aEuro(3)-O-p-trans-coumarate (9), and tricin-7-O-beta-d-glucopyranoside (10). Compounds 1 and 8 are new flavonoids, and 8 and 9 strongly promoted 2BS cell proliferation induced by H2O2.
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