4.4 Article

Two new flavonoids from Centella asiatica (Linn.)

Journal

JOURNAL OF NATURAL MEDICINES
Volume 62, Issue 3, Pages 369-373

Publisher

SPRINGER TOKYO
DOI: 10.1007/s11418-008-0229-0

Keywords

Apiaceae; Centella asiatica; castilliferol; castillicetin; isochlorogenic acid

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Two new flavonoids named castilliferol 1 and castillicetin 2, as well as a known compound, isochlorogenic acid 3, were isolated from the whole plant of Centella asiatica. Isolates 1 and 2 exhibited good antioxidant activity using 2,2-diphenyl-1-picryl hydrazyl radical solution with IC50 values of 23.10 and 13.30, respectively. The structures of these isolates were determined by analytical and spectral data, including 1-D and 2-D NMR spectra.

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