4.4 Article

A new lignan glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd.

Journal

JOURNAL OF NATURAL MEDICINES
Volume 63, Issue 1, Pages 86-90

Publisher

SPRINGER TOKYO
DOI: 10.1007/s11418-008-0289-1

Keywords

Callicarpa japonica Thunb var luxurians Rehd; Verbenaceae; Lignan glucoside; Triterpenoid; Radical-scavenging effect

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A new lignan glucoside (1) was isolated from the stems of Callicarpa japonica Thunb. var. luxurians Rehd. (Verbenaceae), along with six known lignan glucosides and three known triterpenoids. The chemical structure of 1 was characterized as (+)-lyoniresinol 3 alpha-O-(6 ''-3,5-dimethoxy-4-hydroxybenzoyl)-beta-D-glucopyranoside on the basis of spectroscopic data. In addition, the radical-scavenging effect of four lignans on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Among the tested compounds, three compounds, including 1, showed almost the same scavenging activity as that of alpha-tocopherol.

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