4.4 Article

Analysis of CYP3A inhibitory components of star fruit (Averrhoa carambola L.) using liquid chromatography-mass spectrometry

Journal

JOURNAL OF NATURAL MEDICINES
Volume 62, Issue 3, Pages 345-348

Publisher

SPRINGER TOKYO
DOI: 10.1007/s11418-008-0239-y

Keywords

CYP3A; star fruit; Averrhoa carambola; enzyme inhibitor; catechin; LC-MS

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In this study, we analyzed the CYP3A inhibitory components of star fruit Averrhoa carambola L., using liquid chromatography-mass spectrometry (LC-MS). The stereoisomer of procyanidin B1 and B2 and/or the trimer consisting of catechin and/or epicatechin were suggested to be potent inhibitory components.

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