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Applications of Nanotechnology, Next Generation Sequencing and Microarrays in Biomedical Research

Journal

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
Volume 13, Issue 7, Pages 4539-4551

Publisher

AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2013.7522

Keywords

Next Generation Sequencing (NGS); Microarrays; Nanotechnology; Nanoparticles

Funding

  1. National Key Program for Developing Basic Research of China [2010CB933903]
  2. Chinese National Key Project of Science and Technology [2013ZX10004103-002]
  3. NSFC [60927001, 61201033, 61271056]
  4. Hunan Science and Technology Projects [2012SK3105, 2010SK2003]

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Next-generation sequencing technologies, microarrays and advances in bio nanotechnology have had an enormous impact on research within a short time frame. This impact appears certain to increase further as many biomedical institutions are now acquiring these prevailing new technologies. Beyond conventional sampling of genome content, wide-ranging applications are rapidly evolving for next-generation sequencing, microarrays and nanotechnology. To date, these technologies have been applied in a variety of contexts, including whole-genome sequencing, targeted re sequencing and discovery of transcription factor binding sites, noncoding RNA expression profiling and molecular diagnostics. This paper thus discusses current applications of nanotechnology, next-generation sequencing technologies and microarrays in biomedical research and highlights the transforming potential these technologies offer.

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