Journal
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
Volume 12, Issue 8, Pages 6631-6638Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2012.4570
Keywords
Citric Acid; Cobalt Ferrite; Glucose Biosensor; Amperometry
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A novel and practical glucose biosensor was fabricated with immobilization of Glucose oxidase (GOx) enzyme on the surface of citric acid (CA) assisted cobalt ferrite (CF) magnetic nanoparticles (MNPs). This innovative sensor was constructed with glassy carbon electrode which is represented as (GOx)/CA-CF/(GCE). An explicit high negative zeta potential value (-22.4 mV at pH 7.0) was observed on the surface of CA-CF MNPs. Our sensor works on the principle of detection of H2O2 which is produced by the enzymatic oxidation of glucose to gluconic acid. This sensor has tremendous potential for application in glucose biosensing due to the higher sensitivity 2.5 mu A/cm(2)-mM and substantial increment of the anodic peak current from 0.2 mu A to 10.5 mu A.
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