Journal
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
Volume 10, Issue 12, Pages 8286-8292Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2010.2676
Keywords
Gold Nanotubes Electrode; Cyclic Voltammetry; Electrochemical Impedance Spectroscopy; Glucose Oxidase; Biosensor
Categories
Funding
- Nation Natural Science of China [50772125]
- Science and Technology Commission of Shanghai [08JC1420700]
- Chinese Academy of Sciences
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A sensitive and effective amperometric glucose biosensor based on gold nanotubes electrode (GNTE) was investigated. Gold nanotubes (GNTs), which were prepared by electroless plating of the metal within the pores of nanoporous polycarbonate (PC) track-etched membranes, were filled into a hollow teflon cylinder to construct a GNTE. Glucose oxidase (GOD) was immobilized on the electrode via glutaraldehyde cross-linkage method. The electrochemical properties were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The k(m) value of the immobilized glucose oxidase on GNTE was 0.47 mM. The biosensor showed a linear range from 0.4 to 11 mM with excellent sensitivity of 8.77 mu A cm(-2) mM(-1) and fast response time within 5 s.
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