Journal
JOURNAL OF NANOPARTICLE RESEARCH
Volume 14, Issue 11, Pages -Publisher
SPRINGER
DOI: 10.1007/s11051-012-1229-2
Keywords
Nanoaerosol; Consumer products; Nanoparticles; Personal exposure; Safety of nanotechnology
Categories
Funding
- National Institute of Environmental Health Sciences (NIEHS) [83469302, NE/H012893]
- US Environmental Protection Agency [P30ES005022]
- UK Natural Environment Research Council (NERC) [P30ES005022]
- New Jersey Agriculture and Experiment Station (NJAES) at Rutgers University
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In this study we quantified exposures to airborne particles ranging from 14 nm to 20 mu m due to the use of nanotechnology-based cosmetic powders. Three nanotechnology-based and three regular cosmetic powders were realistically applied to a mannequin's face while measuring the concentration and size distribution of inhaled aerosol particles. Using these data we calculated that the highest inhaled particle mass was in the coarse aerosol fraction (2.5-10 mu m), while particles <100 nm made minimal contribution to the inhaled particle mass. For all powders, 85-93 % of aerosol deposition occurred in the head airways, while <10 % deposited in the alveolar and <5 % in the tracheobronchial regions. Electron microscopy data suggest that nanomaterials were likely distributed as agglomerates across the entire investigated aerosol size range (14 nm-20 mu m). Thus, investigation of nanoparticle health effects should consider not only the alveolar region, but also other respiratory system regions where substantial nanomaterial deposition during the actual nanotechnology-based product use would occur.
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