☆ 4.2 Article

PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses

PHARMACOGENETICS AND GENOMICS (2015)

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Journal

PHARMACOGENETICS AND GENOMICS
Volume 25, Issue 8, Pages 416-426

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/FPC.0000000000000150

Keywords

Acetaminophen; CYP2E1; drug-induced liver injury; GSTP1; NAPQI; NSAIDs; paracetamol; UGT1A6; UGT1A9

Categories

Biotechnology & Applied Microbiology Genetics & Heredity Pharmacology & Pharmacy

Funding

  1. NIH/NIGMS [R24 GM61374]
  2. Personalized NSAID Therapeutics Consortium [PENTACON: HL117798]
  3. [T32HL007971]
  4. NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [U54HL117798, T32HL007971] Funding Source: NIH RePORTER
  5. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R24GM061374] Funding Source: NIH RePORTER

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