Journal
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
Volume 21, Issue 3, Pages 379-386Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/10837450.2014.999786
Keywords
Biomaterial; drug delivery; gelatin; ocular; particles
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Despite all scientists efforts exerted over the past years, the ocular delivery of drugs remains a great challenge due to several barriers and hurdles faced by this kind of administration. The exploitation of gelatin that has a long history of safe use in pharmaceuticals and which is considered as a GRAS (Generally Regarded As Safe) material by the FDA was not fully achieved in this field. This review summarizes the recent studies and findings where gelatin-based micro- and nanoparticles were used for successful ocular delivery aiming at drawing the attention of researchers and scientists to this valuable biomaterial that has not been fully explored.
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