Journal
JOURNAL OF MOLECULAR MODELING
Volume 14, Issue 6, Pages 471-478Publisher
SPRINGER
DOI: 10.1007/s00894-008-0298-8
Keywords
5-bromo-2; 4-dichloropyrimidine; docking; SLO; QSAR
Ask authors/readers for more resources
The enzyme inhibitory activity of a new group of 2-substituted pyrimido[4,5-b][1,4]benzothiazines on soybean 15-lipoxygenase (15-LO) was evaluated and compared with those of their 4-methyl analogs using ab initio calculations. The results of these studies showed that the lack of 4-methyl substituent in the pyrimido[4,5-b][1,4] benzothiazine molecules greatly reduces their 15-LO inhibitory activities.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available