Journal
JOURNAL OF MOLECULAR MEDICINE-JMM
Volume 92, Issue 3, Pages 201-206Publisher
SPRINGER
DOI: 10.1007/s00109-013-1101-6
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This minireview briefly summarizes the evidence that adenosine, acting on four G-protein coupled receptors, can play physiological roles, but is also critically involved in pathological processes. The factors that decide which of these is the more important in a specific cell or organ are briefly summarized. The fact that drugs that target adenosine receptors in disease will also hit the physiological processes will make drug development more tricky.
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