4.2 Article

One-pot synthesis of N-tert-butyl amides from alcohols, ethers and esters using ZnCl2/SiO2 as a recyclable heterogeneous catalyst

Journal

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
Volume 337, Issue 1-2, Pages 52-55

Publisher

ELSEVIER
DOI: 10.1016/j.molcata.2011.01.013

Keywords

Ritter reaction; Nitriles; Carbocation source; ZnCl2/SiO2

Funding

  1. Yazd University Research Council

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ZnCl2/SiO2 has been found to be an efficient and reusable catalyst for conversion of alcohols, ethers and esters to corresponding amides via the Ritter reaction in high yield. It was found that benzonitrile reacted with tert-butyl acetate faster than the other sources of tert-butyl carbocation. (C) 2011 Elsevier B.V. All rights reserved.

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