Journal
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
Volume 23, Issue 7, Pages 1041-1045Publisher
KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY
DOI: 10.4014/jmb.1212.12042
Keywords
Luminex; xTAG GPP; multiplex; gastroenteritis; infectious diarrhea
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Funding
- Luminex Molecular Diagnostics
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The xTAG (R) Gastrointestinal Pathogen Panel (GPP) is a multiplexed molecular test for 15 gastrointestinal pathogens. The sensitivity and specificity of this test were assessed in 901 stool specimens collected from pediatric and adult patients at four clinical sites. A combination of conventional and molecular methods was used as comparator. Sensitivity could be determined for 12 of 15 pathogens and was 94.3% overall. The specificity across all 15 targets was 98.5%. Testing for the pathogen identified was not requested by the physician in 65% of specimens. The simultaneous detection of these 15 pathogens can provide physicians with a more comprehensive assessment of the etiology of diarrheal disease.
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