Journal
JOURNAL OF MICROBIOLOGICAL METHODS
Volume 107, Issue -, Pages 106-118Publisher
ELSEVIER
DOI: 10.1016/j.mimet.2014.09.009
Keywords
Carbapenemases; Detection; Screening; Phenotypic methods; Molecular methods
Categories
Funding
- Saint-Joseph University Research Council [FPH37]
- Lebanese National Council for Research and Development [02-09-12]
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This review describes the current state-of-art of carbapenemase detection methods. Identification of carbapenemases is first based on conventional phenotypic tests including antimicrobial susceptibility testing, modified-Hodge test and carbapenemase-inhibitor culture tests. Second, molecular characterization of carbapenemase genes by PCR sequencing is essential. Third, innovative biochemical and spectrometric detection may be applied. (C) 2014 Elsevier B.V. All rights reserved.
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