Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 52, Issue 24, Pages 7946-7949Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jm9015334
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By use of chemical enablement and prospective design, it novel series of selective, brain penetrant PDE9A inhibitors have been identified that are capable of producing in vivo elevations of brain cGMP.
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