Journal
JOURNAL OF MEDICAL MICROBIOLOGY
Volume 61, Issue 9, Pages 1330-1334Publisher
SOC GENERAL MICROBIOLOGY
DOI: 10.1099/jmm.0.045047-0
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Echinocandins are first-line agents for treating severe invasive candidiasis. Glucan synthase gene (FKS1) mutations lead to echinocandin resistance but the role of enhanced chitin expression is not well recognized in clinical isolates. We report a case of bloodstream Candida albicans infection with both Fks1 hotspot mutation and elevated cell wall chitin.
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