4.3 Article

Detection of an Ambler class D OXA-48-type β-lactamase in a Klebsiella pneumoniae strain in The Netherlands

Journal

JOURNAL OF MEDICAL MICROBIOLOGY
Volume 60, Issue 5, Pages 677-678

Publisher

MICROBIOLOGY SOC
DOI: 10.1099/jmm.0.028308-0

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Traditionally, bacteria in The Netherlands have low levels of resistance to antibiotics. This report describes what is believed to be the first carbapenem-resistant Klebsiella pneumoniae producing an OXA-48 type beta-lactamase in The Netherlands. The isolate co-produced a CTX-M-15 type beta-lactamase and was recovered from a patient who was transferred from a hospital in India to an intensive care unit in The Netherlands. His recovery in The Netherlands was complicated by pneumonia due to the carbapenem-resistant K. pneumoniae to which he eventually succumbed. Pre-emptive screening for carbapenem-resistant Enterobacteriaceae in selected patients could be imperative to maintain the low prevalence of these highly resistant bacteria in Dutch hospitals.

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