4.5 Article

GROUP A STREPTOCOCCAL BACTEREMIA WITHOUT A SOURCE IS ASSOCIATED WITH LESS SEVERE DISEASE IN CHILDREN

Journal

PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 34, Issue 4, Pages 447-449

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0000000000000587

Keywords

Group A streptococcus; toxic shock syndrome; bacteremia; varicella; necrotizing fasciitis

Funding

  1. Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services [K-08 HS013908]
  2. Pediatric Critical Care Scientist Development Program [K12 5K12HD047349-07]

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We analyzed characteristics of 86 Group A streptococcal bacteremia cases at Boston Children's Hospital from 1992 to2012. Twenty-three percent of children had severe disease, using intensive care unit admission (18), disability (7) or death (2) as indicators. Children with bacteremia without a source (30% of cases) were less likely to have severe disease than children with focal infections in adjusted models.

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