Journal
JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING
Volume 31, Issue 3, Pages 151-159Publisher
SPRINGER HEIDELBERG
DOI: 10.5405/jmbe.902
Keywords
Peripheral nerve injury; Nerve conduit; Electrophysiological measurement; Functional recovery
Categories
Funding
- National Science Council [NSC 99-2321-B-002-043]
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Peripheral nerve injury is a serious health concern for society, affecting 2.8% of trauma patients, many of whom acquire long-term disability, and the related socioeconomic costs are relatively expensive. Current techniques in peripheral nerve repair include the use of autografts and nerve conduits to bridge the nerve gap. Bioengineers have developed a variety of nerve conduits to improve nerve regeneration, as well as employed functionalized bioactive additives to the nerve conduits. Within such a discipline, adequate evaluation methods are extremely important for correctly assessing nerve repair and regeneration. There are histological, electrophysiological or functional analyses. This article reviews the research efforts that integrate bioengineering approaches.
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