4.2 Review

Stochastic aspects of asymmetric autocatalysis and absolute asymmetric synthesis

Journal

JOURNAL OF MATHEMATICAL CHEMISTRY
Volume 48, Issue 2, Pages 457-489

Publisher

SPRINGER
DOI: 10.1007/s10910-010-9680-8

Keywords

Chirality; Autocatalysis; Stochastic kinetics; Markovian jump process; Multimodality; Deterministic kinetics; Polynomial differential equations

Funding

  1. ESF

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The main goal of the present review is to collect in a unified framework the deterministic and stochastic models of emergence and amplification of chirality by mechanisms such as asymmetric autocatalysis and absolute asymmetric synthesis. Empirical approach and modeling have recently provided a good insight into these phenomena. Our groups in Italy and Hungary have a wide variety of expertise both in fields of experiments and modeling. In the last decade important results have been achieved, however, more experiments and more detailed deterministic and stochastic models are needed for a better understanding of details and significance of asymmetric autocatalysis and absolute asymmetric synthesis.

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