Journal
JOURNAL OF MATHEMATICAL BIOLOGY
Volume 58, Issue 1-2, Pages 285-322Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00285-008-0165-3
Keywords
Dynamical hematological diseases; Mathematical modeling
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We review the basic characteristics of four periodic hematological disorders (periodic auto-immune hemolytic anemia, cyclical thrombocytopenia, cyclical neutropenia and periodic chronic myelogenous leukemia) and examine the role that mathematical modeling and numerical simulations have played in our understanding of the origin of these diseases and in the regulation of hematopoiesis.
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