Journal
JOURNAL OF MATHEMATICAL BIOLOGY
Volume 58, Issue 4-5, Pages 545-559Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00285-008-0211-1
Keywords
Computational systems biology; Agent-based modeling; Tumor simulation
Categories
Funding
- NIH [CA 085139, CA 113004]
- Harvard-MIT (HST) Athinoula A. Martinos Center for Biomedical Imaging and the Department of Radiology
- NATIONAL CANCER INSTITUTE [R01CA085139] Funding Source: NIH RePORTER
Ask authors/readers for more resources
Agent-based modeling (ABM) is an in silico technique that is being used in a variety of research areas such as in social sciences, economics and increasingly in biomedicine as an interdisciplinary tool to study the dynamics of complex systems. Here, we describe its applicability to integrative tumor biology research by introducing a multi-scale tumor modeling platform that understands brain cancer as a complex dynamic biosystem. We summarize significant findings of this work, and discuss both challenges and future directions for ABM in the field of cancer research.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available