Journal
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
Volume 28, Issue 11, Pages 1324-1328Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/14767058.2014.953922
Keywords
25-hydroxy vitamin D; alpha-tocopherol; infant; nutrition; preterm; retinol; vitamin deficiency
Categories
Funding
- Research Unit, Ministry of Higher Education and Scientific Research of Tunisia [05/UR 08-08]
Ask authors/readers for more resources
Objective: To look at changes in plasma vitamin A, E and D concentrations during the early postnatal life and to study their link with growth and mortality in Tunisian very low birth weight (VLBW) infants. Patients and methods: A cohort of 607 VLBW infants had been followed from birth until hospital discharge or death. Blood was collected at birth, at time of maximal weight loss and at time of recovering birth weight. Retinol and alpha-tocopherol were analyzed using HPLC and 25 hydroxy vitamin D using radioimmunoassay. Results: Vitamin A, D and E deficiencies were very common at birth (75.9%, 74.1% and 65.2%, respectively). The prevalence's have decreased throughout hospital stay, but remained high at time of recovering birth weight (59.4%, 31.2% and 28.8%, respectively). Vitamin A deficiency was associated with longer hospital stay [OR (95% CI), 1.66 (1.03-2.93)] and vitamin E deficiency was associated with increased neonatal mortality [1.44 (1.01-2.23)]. Conclusions: Current nutritional practices are ineffective to achieve adequate vitamins A, E and D status in Tunisian VLBW infants during the early postnatal life and should be revised. Further work is needed to establish recommended doses of vitamins supplements in these preterm infants.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available