Journal
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
Volume 22, Issue 12, Pages 2781-2789Publisher
SPRINGER
DOI: 10.1007/s10856-011-4454-9
Keywords
-
Funding
- National Natural Science Foundation of China [81071455]
- Shanghai Science and Technology Committee [09441900106]
Ask authors/readers for more resources
Calcium silicate ceramic coatings have received considerable attention in recent years due to their excellent bioactivity and bonding strength. However, their high dissolution rates limit their practical applications. In this study, zinc incorporated calcium silicate based ceramic Ca2ZnSi2O7 coating was prepared on Ti-6Al-4V substrate via plasma spraying technology aiming to achieve higher chemical stability and additional antibacterial activity. Chemical stability of the coating was assessed by monitoring mass loss and ion release of the coating after immersion in the Tris-HCl buffer solution and examining pH value variation of the solution. Results showed that the chemical stability of zinc incorporated coating was improved significantly. Antimicrobial activity of the Ca2ZnSi2O7 coating was evaluated, and it was found that the coating exhibited 93% antibacterial ratio against Staphylococcus aureus. In addition, in vitro bioactivity and cytocompatibility were confirmed for the Ca2ZnSi2O7 coating by simulated body fluid test, MC3T3-E1 cells adhesion investigation and cytotoxicity assay.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available