Journal
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
Volume 21, Issue 11, Pages 2947-2953Publisher
SPRINGER
DOI: 10.1007/s10856-010-4148-8
Keywords
3D powder printing; Magnesium phosphate cement; Struvite; Bone replacement material
Funding
- Deutsche Forschungsgemeinschaft [DFG Gb1/11-1, DFG Mu1803/7-1, DFG Kl2400/1-2]
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Synthetic bone replacement materials are of great interest because they offer certain advantages compared with organic bone grafts. Biodegradability and preoperative manufacturing of patient specific implants are further desirable features in various clinical situations. Both can be realised by 3D powder printing. In this study, we introduce powder-printed magnesium ammonium phosphate (struvite) structures, accompanied by a neutral setting reaction by printing farringtonite (Mg(3)(PO(4))(2)) powder with ammonium phosphate solution as binder. Suitable powders were obtained after sintering at 1100A degrees C for 5 h following 20-40 min dry grinding in a ball mill. Depending on the post-treatment of the samples, compressive strengths were found to be in the range 2-7 MPa. Cytocompatibility was demonstrated in vitro using the human osteoblastic cell line MG63.
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