4.3 Article

Gd(III)-doped carbon dots as a dual fluorescent-MRI probe

Journal

JOURNAL OF MATERIALS CHEMISTRY
Volume 22, Issue 44, Pages 23327-23330

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2jm35592b

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Funding

  1. Operational Program Research and Development for Innovations - European Regional Development Fund [CZ.1.05/2.1.00/03.0058]
  2. Operational Program Education for Competitiveness - European Social Fund of the Ministry of Education, Youth and Sports of the Czech Republic [CZ.1.07/2.3.00/20.0017, CZ.1.07/2.3.00/20.0155]
  3. project of the Grant Agency of the Academy of Sciences of the Czech Republic [KAN115600801]
  4. King Abdullah University of Science and Technology (KAUST) [KUS-C1-018-02]

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We describe the synthesis of Gd(III)-doped carbon dots as dual fluorescence-MRI probes for biomedical applications. The derived Gd(III)-doped carbon dots show uniform particle size (3-4 nm) and gadolinium distribution and form stable dispersions in water. More importantly, they exhibit bright fluorescence, strong T1-weighted MRI contrast and low cytotoxicity.

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