Journal
JOURNAL OF MATERIALS CHEMISTRY
Volume 22, Issue 13, Pages 6139-6147Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2jm14635e
Keywords
-
Funding
- National Basic Research Program of China [2011CB933700]
- Hi-tech Research and Development Program of China [2009AA03Z330]
- China Postdoctoral Science Foundation [20100480706]
- Anhui Provincial Education Department [KJ2010ZD09]
Ask authors/readers for more resources
A novel strategy is proposed to facilely hybridize the single-walled carbon nanotubes (SWCNTs) and gold nanoparticles (Au NPs) with the assistance of a mild O-2-plasma process and annealing at 500 degrees C in air. An immunosensor was constructed by the SWCNT-Au network bridging an interdigital electrode. The O-2-plasma-oxidized SWCNTs can easily assemble positively charged Au NPs with a high-density and uniform morphology. The annealing leads to surface melting and aggregation of the Au NPs and makes the survival of the SWCNTs much less likely, moreover, it helps to remove any impurities adsorbed on the SWCNT-Au and to form a good contact between the network and the electrode. The annealing-induced alterations result in an interesting power-law current-voltage behavior because of the Au NPs cotunneling effects and its energy-band modulation of the SWCNTs, and greatly amplify the sensitivity on antibody-antigen interactions. The sensor realized high-sensitive, rapid, and selective detections of Salmonella enteritidis flagellin (SEF) and Staphylococcus aureus enterotoxins A (SEA), which was functionalized with the SEF antibody (anti-SEF) and the SEA antibody (anti-SEA), respectively. The results demonstrate a detection limit of at least 2 ng mL(-1) in 5 min incubation for the antibody-antigen reaction. The proposed strategy represents a novel, robust, and simple way to establish immunosensor chips.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available