Journal
JOURNAL OF MATERIALS CHEMISTRY
Volume 21, Issue 42, Pages 16869-16872Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1jm11869b
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Funding
- National Creative Research Initiative [R16-2002-003-01001-0]
- Strategic Research [2010-0029138]
- World Class University of the National Research Foundation of Korea (NRF) [R31-10013]
- Hanwha Chemical Co.
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Multifunctional nanocomposite nanoparticles for simultaneous fluorescence and magnetic resonance (MR) imaging, and pH-sensitive drug release were fabricated by immobilizing pH responsive hydrazone bonds, magnetite nanoparticles and fluorescent dyes in mesoporous silica nanoparticles. pH dependent release of doxorubicin was demonstrated and the nanocomposite nanoparticles show fluorescence emission and MR contrast effect.
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