Journal
JOURNAL OF MATERIALS CHEMISTRY
Volume 21, Issue 45, Pages 18154-18173Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1jm13700j
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Funding
- National Basic Research Program of China [2010CB732400]
- National Natural Science Foundation of China [20821063, 21005037]
- PhD Fund for Young Teachers [20100091120034]
- Fundamental Research Funds for the Central Universities [1117020501]
- Natural Science Foundation of Jiangsu [BK2010193]
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Developing sensitive and specific sensing strategies for probing the chemical and biological events in/at a living cell can ultimately contribute to the understanding of life processes. These strategies are also beneficial to early diagnosis of diseases for early and successful treatment. Biofunctionalization of nanoparticles can integrate remarkable properties of both biological components and nanoparticles, thus providing a promising platform for tracing the recognition and transduction processes and improving the sensing performance. This Feature Article reviews the current research regarding the biofunctionalization strategies, and the usage of the bionanocomposites in the arena of cytosensing and cell surface carbohydrate assay.
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