Journal
JOURNAL OF MATERIALS CHEMISTRY
Volume 20, Issue 5, Pages 880-883Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b916619j
Keywords
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Funding
- National Natural Science Foundation of China [20775019, 20735002]
- National Basic Research Program of China [2010CB732403]
- Hi-Tech Research and Development Program of China [2006AA09Z168]
- Natural Science Foundation of Qingdao [08-1-3-32-JCH]
- Natural Science Foundation of Shandong province [Y2006B01]
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In this work, we report a facile approach for imprinting protein based oil self-polymerization of dopamine in the presence of template protein on the Fe3O4 nanoparticles (NPs) surface. Dopamine, commonly known as a neurotransmitter, is also a small-molecule mimic of the adhesive proteins of Mussels. Self-polymerization of dopamine can produce a thin polydopamine (PDA) layer on Fe3O4 NPs surface. During the self-polymerization of dopamine, some template protein molecules were embedded in the PDA layer. After the removal of these embedded protein molecules, the protein imprinted sites are created. The prepared imprinted Fe3O4@PDA NPs shows high binding capacity and acceptable specific recognition behavior towards template proteins.
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