Post-synthetic modification of the metal-organic framework compound UiO-66

Post-synthetic modification is a viable route for the introduction of surface sites with new chemical properties in metal-organic framework compounds. Herein we demonstrate that it is possible to perform covalent post-synthetic modifications of the UiO-66-NH(2) MOF with four different acid anhydrides. FT-IR is employed to monitor the reactions and the extent of reaction depends on the bulkiness of the anhydrides. For the smallest one, acetic anhydride, 100% conversion to UiO-66-NHCOCH(3) was observed.