4.3 Article

Synthesis and bio-functionalization of multifunctional magnetic Fe3O4@Y2O3:Eu nanocomposites

Journal

JOURNAL OF MATERIALS CHEMISTRY
Volume 19, Issue 27, Pages 4695-4700

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b901427f

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Funding

  1. National Institute of Environmental Health Sciences (NIEHS), NIH [5 P42 ES004699]
  2. National Research Initiative of the USDA Cooperative State Research, Education and Extension Service [2009-35603-05070]
  3. NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [P42ES004699] Funding Source: NIH RePORTER

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A facile homogenous precipitation method has been developed for the synthesis of multifunctional, magnetic, luminescent nanocomposites with Fe3O4 nanoparticles as the core and europium-doped yttrium oxide (Y2O3:Eu) as the shell. The nanocomposites showed both super-paramagnetic behavior and unique europium fluorescence properties with high emission intensity. Their surface has been modified with a bifunctional ligand, p-aminobenzoic acid (PABA), and further biofunctionalized with biotin; the nanocomposites showed specific targeting for avidin-coupled polystyrene beads.

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